李蕾

来源 :       作者 :  生化学院办公室      时间 : 2023-08-31     点击数:21097    打印

26941

个人简介

198507月毕业于江西师范大学化学系。1985-2005年在赣南师范大学化学系工作,其中19959月至19967月、20009月至20017月在北京大学化学与分子工程学院从事访问学者研究工作;2003年晋升教授;2005年入职嘉兴学院,201111月至20128月在科技部高新技术产业化司挂职;现为应用化学系二级教授,南湖学者特聘教授。

主持完成国家自然科学基金面上项目、浙江省科技计划重点项目等省部级课题20余项,主要参与完成国家自然科学基金、浙江省重点研发计划等课题20余项。在Chem. Sci.Anal. Chem.Chem. Commun.ACS Sensors Biosens. Bioelectron. Sensor. Actuat. B: Chem.Anal. Chim. ActaAnalystTalantaMicrochim. Acta等期刊上发表论文150余篇,其中在SCI收录期刊上发表研究论文100余篇;申请国家发明专利30余项,其中授权发明专利20余项。主编出版大学化学实验教材2部;参与制定中华人民共和国出入境检验检疫行业标准3项;获国家教育教学成果奖二等奖1项、浙江省教育教学成果特等奖1项、二等奖2项,中国有色金属工业学会科学技术成果二等奖1项。浙江工业大学、浙江师范大学、江西理工大学、常州大学等兼职硕士生导师,已指导毕业硕士研究生70余名。

联系方式

Email: lei.li@zjxu.edu.cn

 

主讲课程

分析化学、仪器分析、分析化学实验、仪器分析实验

研究方向

1. 分子识别与分离分析技术

2. 微纳功能材料及其应用

 

主持项目

1. 基于烯基离子液体的磁性分子印迹固相萃取及其在芳香胺检测中的应用研究(国家自然科学基金面上项目, No. 21677060

2. 基于双功能烯基染料离子液体的分子印迹荧光传感器构建策略及其检测硝基酚类化合物的研究(浙江省自然科学基金探索项目, No. LY20B050009

3. 农产品中含潜在高危隐患因子的快速捕集与超高灵敏检测关键技术研究(浙江省科技厅公益技术项目, No. 2015C32067

4. 电纺丝纳米纤维-分子印迹膜在环境样品前处理中的应用研究(国家自然科学基金面上项目,No. 21177049

5. 食品安全分析中禁用或滥用雌激素的样品前处理共性关键新技术研究(浙江省公益技术研究项目,No. 2011C22096

 

代表性论文(近五年)

1. Y. Ju, Y. Yang *, Q. Tang, M. Wang, Y. Zeng, Z. Zhang, Y. Zhai, H. Wang, L. Li*. Fluorometric detection of alpha-fetoprotein based on the use of a novel organic compound with AIE activity and aptamer-modified magnetic microparticles, Anal. Chim. Acta, 2023, 1278, 34692.

2. J. Zhang, Y. Zeng*, L. Chen, X. Lei, Y. Yang, Z. Chen*, L. Guo, L. Li*, A novel core-shell composite of PCN-222@MIPIL for ultrasensitive electrochemical sensing 4-nonylphenol, Environ. Res., 2023, 225, 115499.

3. S. Chen, Q. Tang, Y. Zeng*, Y. Yang, T. Zhu, H. Wang, L. Guo, L. Li*, Z. Qian*, A novel fluorescence aptasensor based on PCN-223 as an efficient quencher for sensitive determination of prostate-specific antigen, Microchim. Acta, 2023, 190, 70.

4. T. Zhu, Q. Tang, Y. Zeng*, S. Chen, Y. Yang, H. Wang, J. Chen*, L. Guo, L. Li*, Sensitive determination of prostate-specific antigen with graphene quantum dot-based fluorescence aptasensor using few-layer V2CTx MXene as quencher, Spectrochim. Acta A, 2023, 293, 122474.

5. W. Xie, Y. Ju, J. Zhang, Y. Yang*, Y. Zeng, H. Wang, L. Li*. Highly sensitive and specific determination of imidacloprid pesticide by a novel Fe3O4@SiO2@MIPIL fluorescent sensor, Anal. Chim. Acta, 2022, 1195, 339449.

6. G. Zhou*, X. Lu, M. Yuan, T. Li, L. Li*. Enzymatic cycle-inspired dynamic biosensors affording no false-positive identification. Anal. Chem., 2021, 93, 15482-15492.

7. L. Liu#, M. Yuan#, Y. Jin, G. Zhou*, T. Li, L. Li*, H. Peng*, W. Chen. A tunable dual-effector allostery system for nucleic acid analysis with enhanced sensitivity and extended dynamic range, Anal. Chem., 2021, 93, 8170-8177.

8. X. Lei, Z. Deng, Y. Zeng*, S. Huang, Y. Yang, H. Wang, L. Guo, L. Li*, A novel composite of conductive metal organic framework and molecularly imprinted poly (ionic liquid) for highly sensitive electrochemical detection of bisphenol A, Sensor. Actuat. B: Chem., 2021, 339, 129885.

9. Y. Zhai, X. Wang, Y. Chen, X. Sang, H. Liu*, J. Sheng, Y. Wu, X. Wang, L. Li*, Multiscale-structured polyvinylidene fluoride/polyacrylonitrile/vermiculite nanosheets fibrous membrane with uniform Li+ flux distribution for lithium metal battery, J. Membrane Sci., 2021, 621, 118996.

10. B. Liu, X. Wang, H. Liu*, Y. Zhai, L. Li*, H. Wen*, 2D MOF with electrochemical exfoliated graphene for nonenzymatic glucose sensing: Central metal sites and oxidation potentials, Anal. Chim. Acta, 2020, 1122, 9-19.

11. X. Lu, L. Wang, Q. Chen, Y. Wang, Z. Cao, G. Zhou*, L. Li*, A biosensor based on multifunctional allostery for dynamic analysis of circulating tumor DNA, Chem. Commun., 2020, 56, 4184-4187.

12. X. Lu, G. Zhou, J. Zhang, W. Xie, Y. Yang*, Y. Zeng, Z. Zhang, H. Wang, L. Li*, Highly sensitive determination of 2,4,6-trichlorophenol by using a novel SiO2@MIPIL fluorescence sensor with a double recognition functional monomer, ACS Sensors, 2020, 5, 1445-1454.

13. H. Dai, Z. Deng, Y. Zeng*, J. Zhang, Y. Yang, Q. Ma, W. Hu, L. Guo, L. Li*, S. Wan, H. Liu, Highly sensitive determination of 4-nitrophenol with coumarin-based fluorescent molecularly imprinted poly (ionic liquid), J. Hazard. Mater., 2020, 398, 122854.

14. Y. Lu, J. Hu, Y. Zeng*, Y. Zhu, H. Wang, X. Lei, S. Huang, L. Guo, L. Li*, Electrochemical determination of rutin based on molecularly imprinted poly (ionic liquid) with ionic liquid-graphene as a sensitive element, Sensor. Actuat. B: Chem., 2020, 311, 127911.

15. X. Lu, G. Zhou*, Y. Zeng, Z. Yin , Z. Zhang , L. Guo, Y. Zhai , Y. Yang , H. Wang, L. Li*, Single-step multivalent capture assay for nucleic acid detection with dual-affinity regulation using mutation inhibition and allosteric activationChem. Sci., 2019, 10, 5025-5030.

16. X. Lu, G. Zhou*, Y. LuL. Li*, Stem-loop clutch probes for sequence-specific dsDNA analysis with improved single-mismatch selectivity, Chem. Commun., 2019, 55, 7514-7517.

17. J. Hu, H. Dai, Y. Zeng*, Y. Yang, H. Wang, X. Zhu, L. Li*, G. Zhou, R. Chen*, L. Guo, A cross-linker-based poly(ionic liquid) for sensitive electrochemical detection of 4-nonylphenol, Nanomaterials, 2019, 9, 513.

18. D. Liu, Y. Zeng, G. Zhou, X. Lu, D. Miao, Y. Yang*, Y. Zhai, J. Zhang, Z. Zhang, H. Wang, L. Li*, Fluorometric determination of cardiac myoglobin based on energy transfer from a pyrene-labeled aptamer to graphene oxide, Microchim. Acta, 2019, 186, 287.

19. Y. Yang, Y. Zeng*, C.i Tang, X. Zhu, X. Lu, L. Liu, Z. Chen, L. Li*, Voltammetric determination of 5-hydroxytryptamine based on the use of platinum nanoparticles coated with molecularly imprinted silica, Microchim. Acta, 2018, 185, 219.

20. X. Zhu, Y. Zeng*, Z. Zhang, Y. Yang, Y. Zhai, H. Wang, L. Liu, J. Hu, L. Li*, A new composite of graphene and molecularly imprinted polymer based on ionic liquids as functional monomer and cross-linker for electrochemical sensing 6-benzylaminopurine, Biosens. Bioelectron., 2018, 108, 38-45.

21. H. Yan, X. Tang, X. Zhu, Y. Zeng*, X. Lu, Z. Yin, Y. Lu, Y. Yang, L. Li*, Sandwich-type electrochemical immunosensor for highly sensitive determination of cardiac troponin I using carboxyl-terminated ionic liquid and helical carbon nanotube composite as platform and ferrocenecarboxylic acid as signal label, Sensor. Actuat. B: Chem., 2018, 277, 234-240.

22. X. Lu, Y. Yang, Y. Zeng, L. Li*, X. Wu*, Rapid and reliable determination of p-nitroaniline in wastewater by molecularly imprinted fluorescent polymeric ionic liquid microspheres, Biosens. Bioelectron., 2018, 99, 47-55.

23. Z. Yin*, S. Cheng, L. Xu, H. Liu, K. Huang, L. Li*, Y. Zhai, Y. Zeng, H. Liu, Y. Shao*, Z. Zhang, Y. Lu. Highly sensitive and selective sensor for sunset yellow based on molecularly imprinted polydopamine-coated multi-walled carbon nanotubes, Biosens. Bioelectron., 2018, 100, 565-570.

24. Z. Zhang*, H. Wang, H. Wang, C. Wu, M. Li, L. Li*, Fabrication and evaluation of molecularly imprinted magnetic nanoparticles for elective recognition and magnetic separation of lysozyme in human urine. Analyst, 2018, 143, 5849-5856.

 

授权专利(近三年)

1. 一种MFI-PAN隔膜及其制备方法和应用,发明专利,授权时间:2022.

2. 基于多价捕获并放大输出信号的生物靶标分子检测方法,发明专利,授权时间:2022.

3. 一种基于多支杂交链式反应的核酸检测方法及应用,发明专利,授权时间:2022.

4. 一种基于CeO2子点荧光检测环境水样中4-硝基苯酚的方法,发明专利,授权时间:2022.

5. 一种电化学免疫传感器及其制备方法和应用,发明专利,授权时间:2021.

6. 一种金属有机框架表面分子印迹聚合物及其制备方法和应用,发明专利,授权时间:2021.

7. 一种荧光功能单体 分子印迹聚合物及其制备方法和应用,发明专利,授权时间:2020.

8. 一种磁性介孔氧化硅分子印迹聚合物及其制备方法和应用, 发明专利, 授权时间:2019.

9.  一种静电纺丝-电动喷涂装置及其应用,发明专利,授权时间:2019.

 

获奖情况

1. 基于化工与制药大类人才培养的突破构建融合实验教学体系探索与实践,浙江省教学成果二等奖,浙江省人民政府,时间:2022,排名:1/10

2. 传承·践行·创新:红船精神五化育人体系的构建与实践,国家教育教学成果二等奖,教育部,时间:2023,排名:7/10

3. 红船精神育人体系的构建与实践   ,浙江省教育教学成果特等奖,浙江省人民政府,时间:2022,排名:7/10

4. 硒元素在功能性食品中应用的关键技术及其质量控制标准,中国有色金属工业科学技术二等奖,时间:2020.12,排名:4/12

5. Single-step multivalent capture assay for nucleic acid detection with dual-affinity regulation using mutation inhibition and allosteric activation,嘉兴市自然科学学术一等奖,时间:2019,排名:2/3

 

社会兼职

兼任浙江省化学类与化工制药类教学指导委员会委员、浙江省研究生教育学会理事、浙江省分析测试协会理事、浙江省高等教育学会产学研合作教育分会理事、青海省人社厅科技成果转化顾问、嘉兴市分子识别材料与传感技术重点实验室副主任等职。

联系方式

地址:浙江省嘉兴市广穹路899号
电话:0573-83643264
就业单位联系电话:0573-83640220
传真:0573-83642282
电子邮件:zjxu@zjxu.edu.cn
学院纪委邮箱:shjw@zjxu.edu.cn

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